ABSTRACT
Diabetes mellitus (DM) is one of the most important chronic diseases currently threatening human health worldwide.However,Diabetic kidney disease (DKD) is one of the main microvascular complications of DM;Vitamin D is a steroid hormone that is expressed in bone,kidney,intestines and other tissues.Vitamin D not only plays an important role in regulating calcium and phosphorus metabolism,but also involves the multiple biological effects of immune regulation,inflammatory response,cell proliferation and differentiation.In this paper,the effects of vitamin D on DKD and its research progress are discussed.
ABSTRACT
Objective To investigate the pathogens,clinical characteristic and therapeutic method of acute kidney injury(AKI) Methods The morbidity,composition of pathogeny,staging and prognosis of 624 cases with AKI recruited by our department from January 1999 to December 2009,to evaluate the impacts of possible predisposing factors.Results The mortality rate of AKI was 19.6％(122/624),The mortality in the staging of exhaustion,damage,risk were 37.8％,33.4％ and 6.7％,respectively.Of the 624 patients there were 21 cases (3.4％) discharged due to exacerbation,29 cases (4.7％) maintained the status quo,and 452 cases (72.4％) cured or improved;Among 138 patients with blood purification there vere 116 cascs(84.1 ％)cured or improved and 22 cases (90.9％) with long term blood purification cured or improved.The pathogenyof the non-elderly group (＜60 years old)were original diseases and collapse,and the pathogeny of the elderly group (≥60 years old)were original diseases.Conclusions AKI is serious with high incidence and mortality in hospitalized patients.The efficacy of long-term blood purification is better than common treatment.Early prevention,early diagnosis and active intervention will help to increase survival rate of AKI aud improve prognosis.